Structure via PubChem · Public domain (PubChem)
tiadenol
Sign in to saveTiadenol is a hypolipidemic agent.
In the Vinony graph
Within Vinony's link graph, tiadenol is referenced by 90 other articles, and connects out to liver, medication and circulatory system.
Vinony files it under Chemical pages without DrugBank identifier, Diols and Drugboxes which contain changes to watched fields.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C14H30O2S2
- Molecular weight
- 294.5 g/mol
- IUPAC name
- 2-[10-(2-hydroxyethylsulfanyl)decylsulfanyl]ethanol
- SMILES
- C(CCCCCSCCO)CCCCSCCO
- InChIKey
- WRCITXQNXAIKLR-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 91.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
86 papers- Tiadenol-mediated induction of peroxisomal enzymes in cultured C3H/10T1/2CL8 cells and in chemically transformed C3H/10T1/2 MCA16 cells.International journal of cancer · 1985
- Antilipolytic activity of tiadenol-nicotinate in isolated fat cells: a comparison with its parent drugs.Drugs under experimental and clinical research · 1985
- Experimental studies on pharmacology, metabolism and toxicology with tiadenol-disulfoxide. Dissociation of lipid lowering effects and the induction of peroxisomal and microsomal drug-metabolizing enzymes.Arzneimittel-Forschung · 1987
- Carboxylic metabolites of tiadenol as "proximate" inducers of hepatic peroxisomal beta-oxidation activity.Pharmacological research communications · 1988
- Effects of tiadenol and di-(2-ethylhexyl)phthalate on the metabolism of phosphatidylcholine and phosphatidylethanolamine in the liver of rats: comparison with clofibric acid.Biochemical pharmacology · 1999
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 294.169
Show 3 more facts
- chemical formula
- C₁₄H₃₀O₂S₂
- canonical SMILES
- C(CCCCCSCCO)CCCCSCCO
- subject has role
- hypolipidemic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Watchedfields = changed | verifiedrevid = 443582176 | IUPAC_name = 2,2'-[decane-1,10-diylbis(thio)]diethanol | image = Tiadenol.png | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “tiadenol” article, available under the CC BY-SA 4.0 licence.