Skip to content
EntityQ416414· pop 18· linked from 482 articles

Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. A derivative of benzamide, tiapride is chemically and functionally similar to other benzamide antipsychotics such as sulpiride and amisulpride known for their dopamine antagonist effects.

Wikidata facts

Mass
328.146
Show 4 more facts
Commons category
Tiapride
chemical formula
C₁₅H₂₄N₂O₄S
canonical SMILES
CCN(CC)CCNC(=O)C1=C(C=CC(=C1)S(=O)(=O)C)OC
isomeric SMILES
CCN(CC)CC/N=C(/C1=CC(=CC=C1OC)S(=O)(=O)C)\O
Sources (3)

via Wikidata · CC0

~8 min read

Encyclopedic overview

10 sections
Contents
  • Medical uses
  • Alcoholism
  • Agitation and aggression
  • Movement disorders
  • Side effects
  • Pharmacodynamics
  • Pharmacokinetics
  • Availability
  • See also
  • References

Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly. A derivative of benzamide, tiapride is chemically and functionally similar to other benzamide antipsychotics such as sulpiride and amisulpride known for their dopamine antagonist effects.

==Medical uses==

Excerpted from Wikipedia’s “tiapride” article, available under the CC BY-SA 4.0 licence.