TLN1

Name

talin 1

Type

protein-coding

Position

35,696,925–35,732,212 (−)

Aliases

ILWEQ, TLN, talin-1

Ensembl

ENSG00000137076

RefSeq RNA

NM_006289.4

RefSeq protein

NP_006280.3

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009].

via MyGene.info

Gene · Ensembl

talin 1

Symbol

TLN1

Biotype

Protein coding

Organism

Homo sapiens

Location

9:35,696,925-35,732,212

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein TLN1 PDB 1mix.png

via Wikidata · CC0