TMC2
Sign in to saveAlso known as C20orf145, dJ686C3.3, transmembrane channel like 2
Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.
In the Vinony graph
Within Vinony's link graph, TMC2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 6 Wikipedia language editions.
Gene data
TMC2- Name
- transmembrane channel like 2
- Type
- protein-coding
- Position
- 2,536,573–2,643,580 (+)
- Aliases
- C20orf145
- Ensembl
- ENSG00000149488
- RefSeq RNA
- NM_080751.3, XM_005260660.5, XM_054322937.1, XR_001754152.2, XR_008485230.1
- RefSeq protein
- NP_542789.2, XP_005260717.1, XP_054178912.1
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
transmembrane channel like 2
- Symbol
- TMC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:2,536,573-2,643,580
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 25877
- genetic association
- systemic lupus erythematosus
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/117532
- genomic end
- 2643580
- genomic start
- 2536573
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
- expressed in
- caudate nucleus
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.
== Function ==
Excerpted from Wikipedia’s “TMC2” article, available under the CC BY-SA 4.0 licence.