Structure via PubChem · Public domain (PubChem)
トカイニド
Sign in to saveAlso known as Tonocard®, W-36095, 2-amino-N-(2,6-dimethylphenyl)propanamide, Alanyl-2,6-xylidide, 2-Amino-2',6'-propionoxylidide, Tocainide, 2-amino-N-(2,6-Dimethylphenyl)propanamide, 2-Amino-N-(2,6-dimethylphenyl)propionamid
Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States.
Chemical data
- Formula
- C11H16N2O
- Molecular weight
- 192.26 g/mol
- IUPAC name
- 2-amino-N-(2,6-dimethylphenyl)propanamide
- SMILES
- CC1=C(C(=CC=C1)C)NC(=O)C(C)N
- InChIKey
- BUJAGSGYPOAWEI-UHFFFAOYSA-N
- XLogP
- 0.8
- Polar surface area
- 55.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1984
- Admin. routes
- oral
- Indications
- cardiac arrhythmia
via ChEMBL · EBI
Research
513 papers- Tocainide.2006
- A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues.Current medicinal chemistry · 2018
- Tocainide: a new oral antiarrhythmic.Drug intelligence & clinical pharmacy · 1985
- Tocainide. A review of its pharmacological properties and therapeutic efficacy.Drugs · 1983
- Tocainide: a new oral antiarrhythmic agent.Annals of internal medicine · 1985
via PubMed
Wikidata facts
- Subclass of
- anilides
- Mass
- 192.126263
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₁H₁₆N₂O
- medical condition treated
- heart arrhythmia
- canonical SMILES
- CC1=C(C(=CC=C1)C)NC(=O)C(C)N
- World Health Organisation international non-proprietary name
- tocainide
Sources (2)
via Wikidata · CC0
Article · 日本語
トカイニド(Tocainide)は、Ib群の抗不整脈薬である。アメリカ合衆国では、もはや売られていない。
Abstract from DBpedia / Wikipedia · CC BY-SA