TRIM37
Sign in to saveAlso known as MUL, POB1, TEF3, tripartite motif containing 37
Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.
In the Vinony graph
Vinony's link graph records 7 inbound references to TRIM37, and connects out to PubMed, Ensembl genome database project and Wikidata.
It is catalogued under the topic Genes on human chromosome 17.
Vinony links it to 5 Wikipedia language editions.
Gene data
TRIM37- Name
- tripartite motif containing 37
- Type
- protein-coding
- Aliases
- MUL, POB1, TEF3
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. TRIM37 localizes in peroxisomal membranes, and has been implicated in human peroxisomal biogenesis disorders. [provided by RefSeq, Jul 2020].
via MyGene.info
Gene · Ensembl
tripartite motif containing 37
- Symbol
- TRIM37
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:58,982,633-59,106,921
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 9084
- exact match
- identifiers.org/ncbigene/4591
- genomic end
- 57184282
- genomic start
- 57059999
- chromosome
- human chromosome 17
- cytogenetic location
- 17q22
- genetic association
- mulibrey nanism
Sources (6)
via Wikidata · CC0
~2 min read
Encyclopedic overview
7 sectionsContents
- Function
- Role in breast cancer
- Interactions
- See also
- References
- Further reading
- External links
Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.
== Function ==
Excerpted from Wikipedia’s “TRIM37” article, available under the CC BY-SA 4.0 licence.