Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C25H30ClNO3
- Molecular weight
- 428 g/mol
- IUPAC name
- [(1R,5S)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate chloride
- SMILES
- C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O.[Cl-]
- InChIKey
- RVCSYOQWLPPAOA-DHWZJIOFSA-M
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2004
- Admin. routes
- oral
- Indications
- chronic obstructive pulmonary disease, overactive bladder, urgency urinary incontinence, schizophrenia
via ChEMBL · EBI
Research
307 papers- Efficacy and Safety of Xanomeline-Trospium Chloride in Schizophrenia: A Randomized Clinical Trial.JAMA psychiatry · 2024
- Cobenfy (Xanomeline-Trospium Chloride): A New Frontier in Schizophrenia Management.Cureus · 2024
- Xanomeline/Trospium Chloride: First Approval.Drugs · 2025
- Xanomeline and Trospium Chloride.Clinical therapeutics · 2024
- Efficacy of xanomeline and trospium chloride in schizophrenia: pooled results from three 5-week, randomized, double-blind, placebo-controlled, EMERGENT trials.Schizophrenia (Heidelberg, Germany) · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 427.1914215
Show 4 more facts
- canonical SMILES
- C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)OC3CC4CCC(C3)[N+]45CCCC5)O.[Cl-]
- isomeric SMILES
- C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)O[C@H]3C[C@H]4CC[C@@H](C3)[N+]45CCCC5)O.[Cl-]
- chemical formula
- C₂₅H₃₀ClNO₃
- Commons category
- Trospium
via Wikidata · CC0
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