Structure via PubChem · Public domain (PubChem)
zolmitriptan
Sign in to saveAlso known as (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-{[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one, 4-{[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl}oxazolidin-2-one
composé chimique
In the Vinony graph
Within Vinony's link graph, zolmitriptan is referenced by 1,700 other articles, and connects out to tryptamines, N-methylserotonin and serotonin.
It is catalogued under topics including 2-Oxazolidinones, 5-HT1B agonists and 5-HT1D agonists.
Its subject is documented across 19 Wikipedia language editions.
Chemical data
- Formula
- C16H21N3O2
- Molecular weight
- 287.36 g/mol
- IUPAC name
- (4S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1,3-oxazolidin-2-one
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
- InChIKey
- ULSDMUVEXKOYBU-ZDUSSCGKSA-N
- XLogP
- 2.2
- Polar surface area
- 57.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1997
- Admin. routes
- oral, topical
- Indications
- migraine disorder
via ChEMBL · EBI
Research
730 papers- Zolmitriptan.2006
- Zolmitriptan.2026
- Intranasal zolmitriptan.Expert opinion on pharmacotherapy · 2005
- Zolmitriptan (Zomig).Expert review of neurotherapeutics · 2004
- Zolmitriptan: a review of its use in migraine.Drugs · 1999
via PubMed
Wikidata facts
- Mass
- 287.163377
- Has use
- medication
Show 9 more facts
- chemical formula
- C₁₆H₂₁N₃O₂
- significant drug interaction
- phenelzine
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3
- isomeric SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
- World Health Organisation international non-proprietary name
- zolmitriptan
- medical condition treated
- migraine
- stylized name
- ZOLMitriptan
- Commons category
- Zolmitriptan
- defined daily dose
- 2.5
via Wikidata · CC0
Article · Français
Le zolmitriptan est un agoniste sélectif de la sérotonine, il appartient à la famille des triptans et est utilisé pour le traitement des crises de migraine aiguë avec ou sans aura et céphalées de Horton. Le zolmitriptan est commercialisé par AstraZeneca sous les noms de Zomig, Zomigon (Argentine, Canada et Grèce), AscoTop (Allemagne) et Zomigoro (France). En 2008, Zomig a généré près de 154 millions de dollars de chiffre d'affaires.
Abstract from DBpedia / Wikipedia · CC BY-SA