11-deoxycortisol
Sign in to save11-Deoxycortisol, also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid steroid hormone, and a metabolic intermediate toward cortisol. It was first described by Tadeusz Reichstein in 1938 as Substance S, thus has also been referred to as '''Reichstein's Substance S or Compound S'''.
Research
1,684 papers- 11-deoxycortisol positively correlates with T cell immune traits in physiological conditions.EBioMedicine · 2024
- [11-Deoxycortisol].Nihon rinsho. Japanese journal of clinical medicine · 2005
- [11-Deoxycortisol].Nihon rinsho. Japanese journal of clinical medicine · 1995
- [11-deoxycortisol and 21-deoxycortisol].Nihon rinsho. Japanese journal of clinical medicine · 1999
- 11-deoxycortisol is a corticosteroid hormone in the lamprey.Proceedings of the National Academy of Sciences of the United States of America · 2010
via PubMed
Article
5 sectionsContents
- Function
- Clinical significance
- History
- See also
- References
11-Deoxycortisol, also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid steroid hormone, and a metabolic intermediate toward cortisol. It was first described by Tadeusz Reichstein in 1938 as Substance S, thus has also been referred to as '''Reichstein's Substance S or Compound S'''.
==Function== thumb|left|class=skin-invert-image|Steroidogenesis, showing 11-deoxycortisol in the pathway from [[cholesterol to cortisol.]]