۲سی-بی

Also known as 2,5-dimethoxy-4-bromophenethylamine, Nexus, 4-bromo-2,5-dimethoxyphenylethylamine, 4-bromo-2,5-dimethoxyphenethylamine, 2-(4-bromo-2,5-dimethoxyphenyl)ethylamine

2C-B, also known as 4-bromo-2,5-dimethoxyphenethylamine or by names such as Nexus or Erox, is a psychedelic drug of the phenethylamine and 2C families. The drug is used as a recreational drug and is usually taken orally. 2C-B produces hallucinogenic, mild stimulant, and mild entactogenic-like effects. Its hallucinogenic effects at typical doses are milder than those of other psychedelics like LSD or psilocybin.

Key facts

Drug.image: 2C-B.svg
Drug.image_class: skin-invert-image
Drug.width: 225px
Drug.image2: 2C-B-3d-sticks.png
Drug.image_class2: bg-transparent
Drug.width2: 200px
Drug.tradename: Erox; Nexus; Perfomax
Drug.routes_of_administration: Oral, insufflation
Drug.class: Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen; stimulant; Entactogen
Drug.ATC_prefix: None
Drug.legal_AU: Schedule 9
Drug.legal_BR: F2
Drug.legal_CA: Schedule III
Drug.legal_DE: Anlage I
Drug.legal_UK: Class A
Drug.legal_US: Schedule I
Drug.legal_UN: P II
Drug.bioavailability: Low

via Wikipedia infobox

Chemical data

Formula: C10H14BrNO2
Molecular weight: 260.13 g/mol
IUPAC name: 2-(4-bromo-2,5-dimethoxyphenyl)ethanamine
SMILES: COC1=CC(=C(C=C1CCN)OC)Br
InChIKey: YMHOBZXQZVXHBM-UHFFFAOYSA-N
XLogP: 2.1
Polar surface area: 44.5 Å²
H-bond donors: 1
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Research

128 papers

Psilocybin and 2C-B at Encoding Distort Episodic Familiarity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
Acquired synaesthesia following 2C-B use.Psychopharmacology · 2019
Tusi: a new ketamine concoction complicating the drug landscape.The American journal of drug and alcohol abuse · 2023
Mistaking 2C-P for 2C-B: What a Difference a Letter Makes.Journal of analytical toxicology · 2017
Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats-pharmacokinetics, effects on behaviour and thermoregulation.Frontiers in pharmacology · 2023

via PubMed

Wikidata facts

Subclass of: 2C
Has part: nitrogen
Mass: 259.020791
Image: 2CBPowder.jpg

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chemical formula: C₁₀H₁₄BrNO₂
subject has role: aphrodisiac
canonical SMILES: COC1=CC(=C(C=C1CCN)OC)Br
Commons category: 2C-B
discoverer or inventor: Alexander Shulgin
described by source: Phenethylamines I Have Known And Loved

Sources (3)

via Wikidata · CC0

Gallery (5)

Available in 27 languages

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via Wikidata sitelinks · CC0