8-Hydroxyguanosine

Also known as Purine-6,8(1H,9H)-dione, 2-amino-9-.beta.-D-ribofuranosyl- (7CI,8CI), Purine-6,8(1H,9H)-dione, 2-amino-9-.beta.-delta-ribofuranosyl- (7CI,8CI), 7,8-Dihydro-8-oxo-Guanosine, 8-Oxoguanosine

8-Hydroxyguanosine is an RNA nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress causing RNA damage.

Research

621 papers

Salivary 8-hydroxyguanosine levels in smokers and non-smokers with chronic periodontitis.Odontology · 2020
8-Hydroxyguanosine and 8-methoxyguanosine possess immunostimulating activity for B lymphocytes.Cellular immunology · 1985
8-Hydroxyguanosine as a possible RNA oxidative modification marker in urine from colorectal cancer patients: Evaluation by ultra performance liquid chromatography-tandem mass spectrometry.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2020
Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases.Free radical biology & medicine · 2009
Oxidative stress marker 8-hydroxyguanosine is more highly expressed in prostate cancer than in benign prostatic hyperplasia.Molecular and clinical oncology · 2018

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References

8-Hydroxyguanosine is an RNA nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress causing RNA damage.

==See also== 8-Oxo-2'-deoxyguanosine