Structure via PubChem · Public domain (PubChem)
A-84,543
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A-84543 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives.
Chemical data
- Formula
- C11H16N2O
- Molecular weight
- 192.26 g/mol
- IUPAC name
- 3-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]pyridine
- SMILES
- CN1CCC[C@H]1COC2=CN=CC=C2
- InChIKey
- MVLJPWPLDPHKST-JTQLQIEISA-N
- XLogP
- 1.4
- Polar surface area
- 25.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 192.126263132
Show 4 more facts
- chemical formula
- C₁₁H₁₆N₂O
- isomeric SMILES
- CN1CCC[C@H]1COC2=CN=CC=C2
- Commons category
- A-84,543
- canonical SMILES
- CN1CCCC1COc1cccnc1
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
A-84543 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives.
== References ==
Excerpted from Wikipedia’s “A-84,543” article, available under the CC BY-SA 4.0 licence.