abrocitinib
Sign in to saveAbrocitinib, sold under the brand name Cibinqo, is a medication used for the treatment of atopic dermatitis (eczema). It is a Janus kinase inhibitor and it was developed by Pfizer. It is taken by mouth.
Key facts
- Drug.image
- Abrocitinib.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Cibinqo
- Drug.MedlinePlus
- a622008
- Drug.DailyMedID
- Abrocitinib
- Drug.pregnancy_AU
- D
- Drug.routes_of_administration
- By mouth
- Drug.class
- Janus kinase inhibitor
- Drug.ATC_prefix
- D11
- Drug.ATC_suffix
- AH08
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.elimination_half life
- 2.8–5.2 h
- Drug.excretion
- 1.0–4.4% unchanged in urine
- Drug.CAS_number
- 1622902-68-4
- Drug.PubChem
- 78323835
via Wikipedia infobox
Chemical data
- Formula
- C14H21N5O2S
- Molecular weight
- 323.42 g/mol
- IUPAC name
- N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +323.14159591199996
Show 4 more facts
- P2175
- atopic dermatitis
- P366
- medication
- P3493
- boxed warning
via Wikidata · CC0
Article
15 sectionsContents
- Medical uses
- Efficacy of abrocitinib in treating atopic dermatitis
- Side effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- History
- Society and culture
- Legal status
- Other therapeutic effects of abrocitinib
- In pediatric peanut allergy
- Therapy of oral lichen planus
- Improving the lesions of extensive necrobiosis lipoidica
- References
- External links
Abrocitinib, sold under the brand name Cibinqo, is a medication used for the treatment of atopic dermatitis (eczema). It is a Janus kinase inhibitor and it was developed by Pfizer. It is taken by mouth.
The most common side effects include nausea (feeling sick), headache, acne, herpes simplex (viral infection of the mouth or the genitals), increased levels of creatine phosphokinase in the blood (an enzyme released into the blood when muscle is damaged), vomiting, dizziness and pain in the upper belly.