Structure via PubChem · Public domain (PubChem)
acebutolol
Sign in to saveAlso known as IL-17803A, Sectral®, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide, N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide, (+-)-acebutolol, 5'-butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone, 3'-acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide, Acebutololum
Chemical data
- Formula
- C18H28N2O4
- Molecular weight
- 336.4 g/mol
- IUPAC name
- N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
- SMILES
- CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
- InChIKey
- GOEMGAFJFRBGGG-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 87.7 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
1,179 papers- Acebutolol: a review of its pharmacology, pharmacokinetics, clinical uses, and adverse effects.Pharmacotherapy · 1986
- Acebutolol: ten years of experience.American heart journal · 1985
- Acebutolol. A review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia.Drugs · 1985
- Acebutolol.The Medical letter on drugs and therapeutics · 1985
- Effects of acebutolol on the serum lipid profile.Drugs · 1988
via PubMed
~6 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Pharmacology
- Pharmacokinetics
- Chemistry
- References
- External links
{{Drugbox | verifiedrevid = 477237780 | IUPAC_name = (RS)-N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide | image = Acebutolol.svg | image_class = skin-invert-image | image2 = Acebutolol ball-and-stick.png | image_class2 = bg-transparent
| tradename = Sectral, Prent, others | Drugs.com = | MedlinePlus = a687003 | licence_US = Acebutolol | pregnancy_AU = C | pregnancy_US = B | pregnancy_category = | legal_UK = POM | legal_status = Rx-only | routes_of_administration = By mouth, IV
Excerpted from Wikipedia’s “acebutolol” article, available under the CC BY-SA 4.0 licence.