acibenzolar-S-methyl
Also known as S-methyl benzo[d][1,2,3]thiadiazole-7-carbothioate, 1,2,3-benzothiadiazole-7-carboxlic acid thiomethyl ester, 7-(methylthiocarbonyl)-benzo-1,2,3-thiadiazole, S-methyl benzo[1,2,3]thiadiazole-7-carbothioate, benzo-(1,2,3)-thiadiazole-7-carbothioic acid S-methyl ester, BTH
'Acibenzolar-S-methyl' is the ISO common name for an organic compound that is used as a fungicide. Unusually, it is not directly toxic to fungi but works by inducing systemic acquired resistance, the natural defence system of plants.
Article
11 sectionsContents
- History
- Synthesis
- Mechanism of action
- Usage
- In the USA
- In Europe
- Human safety
- Resistance management
- References
- Further reading
- External links
'Acibenzolar-S-methyl' is the ISO common name for an organic compound that is used as a fungicide. Unusually, it is not directly toxic to fungi but works by inducing systemic acquired resistance, the natural defence system of plants.
==History== In the 1980s, researchers at Ciba-Geigy in Switzerland were seeking novel fungicides. They discovered that the methyl ester of 1,2,3-benzothiadiazole-7-carboxylic acid, and many other derivatives, had useful activity on fungal diseases, for example Pyricularia oryzae on rice. In subsequent studies it was shown that the compound responsible for the biological activity was the carboxylic acid itself but that for optimum activity when used commercially it was important to choose a derivative which met requirements of product safety, ease of application and appropriate physical properties for translocation in the crop. After many derivatives of the acid had been tested, the S-methyl thioester was chosen for development under the code name CGA245704. The product was launched in 1996 and is now sold by Syngenta with brand names including Bion and Actigard.