albiglutide
Sign in to saveAlso known as GSK716155
Albiglutide (trade names Eperzan in Europe and Tanzeum in the US) is a glucagon-like peptide-1 agonist (GLP-1 agonist) drug marketed by GlaxoSmithKline (GSK) for treatment of type 2 diabetes. In 2017 GSK announced Albiglutide's withdrawal from the worldwide market for economic reasons, and remaining stocks in the supply chain were effectively depleted by 2018.
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Protein
- First approval
- 2014
- Admin. routes
- parenteral
- Indications
- congestive heart failure, diabetes mellitus, type 1 diabetes mellitus, type 2 diabetes mellitus
via ChEMBL · EBI
Research
307 papers- Albiglutide.2012
- Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial.Lancet (London, England) · 2018
- Albiglutide-induced pancreatitis.Therapeutic advances in drug safety · 2016
- Albiglutide for the management of type 2 diabetes.Expert review of endocrinology & metabolism · 2018
- Brain uptake pharmacokinetics of albiglutide, dulaglutide, tirzepatide, and DA5-CH in the search for new treatments of Alzheimer's and Parkinson's diseases.Tissue barriers · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has use
- medication
Show 5 more facts
- NCI Thesaurus ID
- C78128
- subject has role
- incretins
- medical condition treated
- glucose intolerance
- defined daily dose
- 5.7
- has characteristic
- biopharmaceutical
via Wikidata · CC0
~6 min read
Encyclopedic overview
11 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- References
Albiglutide (trade names Eperzan in Europe and Tanzeum in the US) is a glucagon-like peptide-1 agonist (GLP-1 agonist) drug marketed by GlaxoSmithKline (GSK) for treatment of type 2 diabetes. In 2017 GSK announced Albiglutide's withdrawal from the worldwide market for economic reasons, and remaining stocks in the supply chain were effectively depleted by 2018.
==Medical uses== Albiglutide was used for the treatment of type 2 diabetes in adults. It can be used alone (if metformin therapy is ineffective or not tolerated) or in combination with other antidiabetic drugs, including insulins.
Excerpted from Wikipedia’s “albiglutide” article, available under the CC BY-SA 4.0 licence.