Structure via PubChem · Public domain (PubChem)
almokalant
Sign in to saveAlso known as H 234/09
Almokalant is a drug used to treat arrhythmia. It is a potassium channel blocker. It has been found to have teratogenic effects in rats.
Chemical data
- Formula
- C18H28N2O3S
- Molecular weight
- 352.5 g/mol
- IUPAC name
- 4-[3-[ethyl(3-propylsulfinylpropyl)amino]-2-hydroxypropoxy]benzonitrile
- SMILES
- CCCS(=O)CCCN(CC)CC(COC1=CC=C(C=C1)C#N)O
- InChIKey
- ZMHOBBKJBYLXFR-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 92.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
79 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 352.182064
Show 3 more facts
- chemical formula
- C₁₈H₂₈N₂O₃S
- canonical SMILES
- CCCS(=O)CCCN(CC)CC(COC1=CC=C(C=C1)C#N)O
- subject has role
- antiarrhythmic agent
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | Watchedfields = changed | verifiedrevid = 453369718 | IUPAC_name = 4-(3-{Ethyl[3-(propane-1-sulfinyl)propyl]amino}-2-hydroxypropoxy)benzonitrile | image = almokalant.svg | image_class = skin-invert-image | alt =
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “almokalant” article, available under the CC BY-SA 4.0 licence.