Structure via PubChem · Public domain (PubChem)
آلموتریپتان
Sign in to saveAlso known as Axert®, LAS-31416, PNU-180638E, 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine, Almotriptan
Almotriptan, sold under the brand names Axert and Almogran among others, is a triptan medication used in the treatment of heavy migraine headache.
Chemical data
- Formula
- C17H25N3O2S
- Molecular weight
- 335.5 g/mol
- IUPAC name
- N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CS(=O)(=O)N3CCCC3
- InChIKey
- WKEMJKQOLOHJLZ-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 64.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2001
- Admin. routes
- oral
- Indications
- migraine disorder
via ChEMBL · EBI
Research
311 papers- Almotriptan.2006
- Almotriptan: a review of 20 years' clinical experience.Expert review of neurotherapeutics · 2019
- Almotriptan.2026
- Almotriptan: a review of its use in migraine.Drugs · 2002
- Almotriptan, a new anti-migraine agent: a review.CNS drug reviews · 2002
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 335.166748
- Has use
- medication
Show 8 more facts
- chemical formula
- C₁₇H₂₅N₃O₂S
- Commons category
- Almotriptan
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CS(=O)(=O)N3CCCC3
- World Health Organisation international non-proprietary name
- almotriptan
- medical condition treated
- migraine
- defined daily dose
- 12.5
- subject has role
- serotonin receptor agonists
- significant drug interaction
- linezolid
via Wikidata · CC0