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alvameline

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alvameline

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Alvameline (Lu 25-109) is a M1 receptor agonist and M2/M3 receptor antagonist that was under investigation for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued.

Chemical data

Formula
C9H15N5
Molecular weight
193.25 g/mol
IUPAC name
5-(2-ethyltetrazol-5-yl)-1-methyl-3,6-dihydro-2H-pyridine
SMILES
CCN1N=C(N=N1)C2=CCCN(C2)C
InChIKey
RNMOMKCRCIRYCZ-UHFFFAOYSA-N
XLogP
0.7
Polar surface area
46.8 Ų
H-bond donors
0
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
193.133
Show 4 more facts
canonical SMILES
CCN1N=C(N=N1)C2=CCCN(C2)C
chemical formula
C₉H₁₅N₅
Commons category
Alvameline
different from
alverine
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

Alvameline (Lu 25-109) is a M1 receptor agonist and M2/M3 receptor antagonist that was under investigation for the treatment of Alzheimer's disease, but produced poor results in clinical trials and was subsequently discontinued.

== See also == Milameline Sabcomeline Tazomeline Xanomeline

Excerpted from Wikipedia’s “alvameline” article, available under the CC BY-SA 4.0 licence.

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