Structure via PubChem · Public domain (PubChem)
amentoflavone
Sign in to saveAlso known as 3',8''-Biapigenin, 8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Amentoflavone is a biflavonoid (bis-apigenin coupled at 8 and 3 positions, or 3,8-biapigenin) constituent of a number of plants including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Biophytum sensitivum, Selaginella tamariscina, Hypericum perforatum (St. John's Wort) and Xerophyta plicata.
Chemical data
- Formula
- C30H18O10
- Molecular weight
- 538.5 g/mol
- IUPAC name
- 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
655 papersvia PubMed
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Amentoflavone is a biflavonoid (bis-apigenin coupled at 8 and 3 positions, or 3,8-biapigenin) constituent of a number of plants including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Biophytum sensitivum, Selaginella tamariscina, Hypericum perforatum (St. John's Wort) and Xerophyta plicata.
Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body. It is also an inhibitor of human cathepsin B.
Excerpted from Wikipedia’s “amentoflavone” article, available under the CC BY-SA 4.0 licence.