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ampiroxicam

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EntityQ3614672· pop 10· linked from 281 articles

ampiroxicam

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Also known as CP 65703, carbonic acid ethyl 1-({2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl}oxy)ethyl ester S,S-dioxide, CP-65703

Ampiroxicam (INN) is a non-steroidal anti-inflammatory drug (NSAID). It is a prodrug of piroxicam. It has been studied for potential anticancer activity, but preliminary results did not show evidence of such activity.

Chemical data

Formula
C20H21N3O7S
Molecular weight
447.5 g/mol
IUPAC name
ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1lambda6,2-benzothiazin-4-yl]oxy]ethyl carbonate
SMILES
CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
InChIKey
LSNWBKACGXCGAJ-UHFFFAOYSA-N
XLogP
4
Polar surface area
133 Ų
H-bond donors
1
H-bond acceptors
9
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
447.11
Show 4 more facts
chemical formula
C₂₀H₂₁N₃O₇S
canonical SMILES
CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
World Health Organisation international non-proprietary name
ampiroxicam
Commons category
Ampiroxicam
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Ampiroxicam (INN) is a non-steroidal anti-inflammatory drug (NSAID). It is a prodrug of piroxicam. It has been studied for potential anticancer activity, but preliminary results did not show evidence of such activity.

== References ==

Excerpted from Wikipedia’s “ampiroxicam” article, available under the CC BY-SA 4.0 licence.