APOC2
Sign in to saveAlso known as APO-CII, APOC-II, apolipoprotein C2
protein-coding gene in the species Homo sapiens
Gene data
APOC2- Name
- apolipoprotein C2
- Type
- protein-coding
- Position
- 44,936,126–44,949,585 (+)
- Aliases
- APO-CII, APOC-II
- Ensembl
- ENSG00000234906
- RefSeq RNA
- NM_000483.5
- RefSeq protein
- NP_000474.2
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
apolipoprotein C2
- Symbol
- APOC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:44,936,126-44,949,585
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI