Structure via PubChem · Public domain (PubChem)
atiprosin
Sign in to saveAtiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor antagonist. It also possesses some antihistamine activity, though it is some 15-fold weaker in this regard than as an alpha blocker. It was never marketed.
Chemical data
- Formula
- C20H29N3
- Molecular weight
- 311.5 g/mol
- IUPAC name
- (2S,7R)-3-ethyl-17-methyl-6-propan-2-yl-3,6,10-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),11,13,15-tetraene
- SMILES
- CCN1CCN([C@H]2[C@H]1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- InChIKey
- WXNVFYIBELASJW-QUCCMNQESA-N
- XLogP
- 3.4
- Polar surface area
- 11.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 311.236148
Show 4 more facts
- chemical formula
- C₂₀H₂₉N₃
- canonical SMILES
- CCN1CCN(C2C1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- isomeric SMILES
- CCN1CCN([C@H]2[C@H]1C3=C(C4=CC=CC=C4N3CC2)C)C(C)C
- Commons category
- Atiprosin
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Atiprosin (developmental code name AY-28,228) is an antihypertensive agent which acts as a selective α1-adrenergic receptor antagonist. It also possesses some antihistamine activity, though it is some 15-fold weaker in this regard than as an alpha blocker. It was never marketed.
==See also== Prazosin Ketanserin
Excerpted from Wikipedia’s “atiprosin” article, available under the CC BY-SA 4.0 licence.