Structure via PubChem · Public domain (PubChem)
آویتریپتان
Sign in to saveAvitriptan (; development code BMS-180048) is an antimigraine drug of the triptan family which was never marketed. It acts as a serotonin 5-HT1B and 5-HT1D receptor agonist. The drug reached phase 3 clinical trials prior to the discontinuation of its development.
Chemical data
- Formula
- C22H30N6O3S
- Molecular weight
- 458.6 g/mol
- IUPAC name
- 1-[3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
- SMILES
- CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCCN3CCN(CC3)C4=NC=NC=C4OC
- InChIKey
- WRZVGHXUPBWIOO-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 112 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 458.21
Show 3 more facts
- chemical formula
- C₂₂H₃₀N₆O₃S
- canonical SMILES
- CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCCN3CCN(CC3)C4=NC=NC=C4OC
- Commons category
- Avitriptan
Sources (2)
via Wikidata · CC0