Structure via PubChem · Public domain (PubChem)
بپریدیل
Sign in to saveAlso known as CERM-1978, Vascor®, Bepadin, Bepridil, Vascor
Bepridil (trade name Vascor) is an diamine calcium channel blocker once used to treat angina pectoris. It is no longer sold in the United States.
Chemical data
- Formula
- C24H34N2O
- Molecular weight
- 366.5 g/mol
- IUPAC name
- N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline
- SMILES
- CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
- InChIKey
- UIEATEWHFDRYRU-UHFFFAOYSA-N
- XLogP
- 5.3
- Polar surface area
- 15.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1990
- Admin. routes
- oral
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
1,056 papers- Bepridil.Lancet (London, England) · 1988
- Pharmacology of bepridil.The American journal of cardiology · 1992
- Bepridil therapy: guidelines for patient selection and monitoring of therapy.The American journal of cardiology · 1992
- Bepridil is potent against SARS-CoV-2 in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2021
- Bepridil: a new long-acting calcium channel blocking agent.Drug intelligence & clinical pharmacy · 1987
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 366.267114
- Has use
- medication
Show 7 more facts
- significant drug interaction
- thioridazine
- chemical formula
- C₂₄H₃₄N₂O
- medical condition treated
- angina pectoris
- canonical SMILES
- CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
- defined daily dose
- 0.3
- subject has role
- vasodilator agent
- physically interacts with
- Potassium voltage-gated channel subfamily Q member 4
via Wikidata · CC0