Structure via PubChem · Public domain (PubChem)
bepridil
Sign in to saveAlso known as CERM-1978, Vascor®, Bepadin, Vascor
Bepridil (trade name Vascor) is an diamine calcium channel blocker once used to treat angina pectoris. It is no longer sold in the United States.
Chemical data
- Formula
- C24H34N2O
- Molecular weight
- 366.5 g/mol
- IUPAC name
- N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline
- SMILES
- CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
- InChIKey
- UIEATEWHFDRYRU-UHFFFAOYSA-N
- XLogP
- 5.3
- Polar surface area
- 15.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1990
- Admin. routes
- oral
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
1,056 papers- Bepridil.Lancet (London, England) · 1988
- Pharmacology of bepridil.The American journal of cardiology · 1992
- Bepridil therapy: guidelines for patient selection and monitoring of therapy.The American journal of cardiology · 1992
- Bepridil is potent against SARS-CoV-2 in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2021
- Bepridil: a new long-acting calcium channel blocking agent.Drug intelligence & clinical pharmacy · 1987
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 366.267114
- Has use
- medication
Show 7 more facts
- significant drug interaction
- thioridazine
- chemical formula
- C₂₄H₃₄N₂O
- medical condition treated
- angina pectoris
- canonical SMILES
- CC(C)COCC(CN(CC1=CC=CC=C1)C2=CC=CC=C2)N3CCCC3
- defined daily dose
- 0.3
- subject has role
- vasodilator agent
- physically interacts with
- Potassium voltage-gated channel subfamily Q member 4
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Ebola research
- SARS-CoV-2 research
- References
- External links
Bepridil (trade name Vascor) is an diamine calcium channel blocker once used to treat angina pectoris. It is no longer sold in the United States.
It is nonselective.
Excerpted from Wikipedia’s “bepridil” article, available under the CC BY-SA 4.0 licence.