Structure via PubChem · Public domain (PubChem)
bifonazole
Sign in to saveAlso known as Bay h 4502, BAY-H-4502, 1-(p,alpha-diphenylbenzyl)imidazole, 1-(alpha-(4-biphenylyl)benzyl)imidazole, 1-[(4-biphenylyl)phenylmethyl]-1H-imidazole, (+-)1-([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole, (+-)-1-(p,alpha-diphenylbenzyl)imidazole
Bifonazole (trade name Canespor among others) is an imidazole antifungal drug used in form of ointments.
In the Vinony graph
Vinony's link graph records 162 inbound references to bifonazole, and connects out to antifungal, International Standard Book Number and digital object identifier.
It is catalogued under topics including 21-Hydroxylase inhibitors, Antifungals and Aromatase inhibitors.
Vinony links it to 20 Wikipedia language editions.
Chemical data
- Formula
- C22H18N2
- Molecular weight
- 310.4 g/mol
- IUPAC name
- 1-[phenyl-(4-phenylphenyl)methyl]imidazole
- SMILES
- C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4
- InChIKey
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N
- XLogP
- 4.8
- Polar surface area
- 17.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- tinea pedis, tinea unguium
via ChEMBL · EBI
Research
473 papers- Otomycosis: Diagnosis and treatment.Clinics in dermatology · 2010
- Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses.Drugs · 1989
- 1-[(Biphenyl-4-yl)(phen-yl)meth-yl]-1H-imidazole (bifonazole).Acta crystallographica. Section E, Structure reports online · 2010
- Butenafine.Drugs · 1998
- Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 310.146999
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₂H₁₈N₂
- World Health Organisation international non-proprietary name
- bifonazole
- canonical SMILES
- C1=CC=C(C=C1)C2=CC=C(C=C2)C(C3=CC=CC=C3)N4C=CN=C4
- Commons category
- Bifonazole
- subject has role
- aromatase inhibitors
via Wikidata · CC0
~2 min read
Encyclopedic overview
7 sectionsContents
- Adverse effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Synthesis
- References
- Further reading
Bifonazole (trade name Canespor among others) is an imidazole antifungal drug used in form of ointments.
It was patented in 1974 and approved for medical use in 1983. There are also combinations with carbamide for the treatment of onychomycosis.
Excerpted from Wikipedia’s “bifonazole” article, available under the CC BY-SA 4.0 licence.
Gallery (2)
Available in 20 languages
- Español
- Français
- Deutsch
- 中文
- 日本語
- Русский
- Português
- العربية
- Azerbaijani
- Bahasa Indonesia
- Hebrew
- Hungarian
- Polski
- Romanian
- Serbian
- Serbian (Latin)
- Tiếng Việt
- Ukrainian
Show 1 more
via Wikidata sitelinks · CC0