Structure via PubChem · Public domain (PubChem)
bisulepin
Sign in to saveAlso known as bisulepine, (3E)-N,N-Dimethyl-3-(5H-thieno[2,3-c][2]benzothiepin-10-ylidene)propan-1-amine
Bisulepin is strong and relatively selective antihistamine (H1 antagonist) with hypnotic, antiadrenergic and very weak anticholinergic and antiserotonergic effects. Bisulepin is marketed in the Czech Republic and Slovakia under the trademark Dithiaden as tablets and injections.
In the Vinony graph
Within Vinony's link graph, bisulepin is referenced by 203 other articles, and connects out to Czech Republic, Slovakia and digital object identifier.
It sits within the topics Antihistamines, Chemical pages without DrugBank identifier and Drugs with no legal status.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C17H19NS2
- Molecular weight
- 301.5 g/mol
- IUPAC name
- (3E)-N,N-dimethyl-3-(5H-thieno[2,3-c][2]benzothiepin-10-ylidene)propan-1-amine
- SMILES
- CN(C)CC/C=C\1/C2=C(SCC3=CC=CC=C31)SC=C2
- InChIKey
- ZLJLUTCIUOCIQM-OVCLIPMQSA-N
- XLogP
- 4.2
- Polar surface area
- 56.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 301.09589160800004
Show 4 more facts
- chemical formula
- C₁₇H₁₉NS₂
- canonical SMILES
- CN(C)CCC=C1C2=C(SCC3=CC=CC=C31)SC=C2
- isomeric SMILES
- CN(C)CC/C=C\1/C2=C(SCC3=CC=CC=C31)SC=C2
- Commons category
- Bisulepin
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
Bisulepin is strong and relatively selective antihistamine (H1 antagonist) with hypnotic, antiadrenergic and very weak anticholinergic and antiserotonergic effects. Bisulepin is marketed in the Czech Republic and Slovakia under the trademark Dithiaden as tablets and injections.
The registered active form is the trans- (i.e. E-) isomer.
Excerpted from Wikipedia’s “bisulepin” article, available under the CC BY-SA 4.0 licence.