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Bornaprolol
Sign in to saveAlso known as C19H29NO2
Bornaprolol is a beta-adrenergic antagonist. ==Synthesis== [[File:Bornaprolol synthesis.svg|thumb|center|500px|ChemDrug Synthesis: Patent:]] The reaction between 2-(Bicyclo[2.2.1]hept-2-yl)phenol [17152-43-1] (1) and epichlorohydrin [106-89-8] (2) in the presence of sodium metal gives (3). Opening of the oxirane by treatment with isopropylamine [75-31-0] (4) completed the synthesis of Bornaprolol (5). ==References==
Chemical data
- Formula
- C19H29NO2
- Molecular weight
- 303.4 g/mol
- IUPAC name
- 1-[2-(2-bicyclo[2.2.1]heptanyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
- SMILES
- CC(C)NCC(COC1=CC=CC=C1C2CC3CCC2C3)O
- InChIKey
- NACJSVRGPPMZRS-UHFFFAOYSA-N
- XLogP
- 4.2
- Polar surface area
- 41.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 303.219829
Show 2 more facts
- chemical formula
- C₁₉H₂₉NO₂
- canonical SMILES
- CC(C)NCC(COC1=CC=CC=C1C2CC3CCC2C3)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Bornaprolol is a beta-adrenergic antagonist. ==Synthesis== [[File:Bornaprolol synthesis.svg|thumb|center|500px|ChemDrug Synthesis: Patent:]] The reaction between 2-(Bicyclo[2.2.1]hept-2-yl)phenol [17152-43-1] (1) and epichlorohydrin [106-89-8] (2) in the presence of sodium metal gives (3). Opening of the oxirane by treatment with isopropylamine [75-31-0] (4) completed the synthesis of Bornaprolol (5). ==References==
Category:Beta blockers Category:N-isopropyl-phenoxypropanolamines
Excerpted from Wikipedia’s “Bornaprolol” article, available under the CC BY-SA 4.0 licence.