carprofen
Sign in to saveAlso known as Ro-205720000, 6-chloro-alpha-methyl-9H-carbazole-2-acetic acid, (+-)-6-chloro-alpha-methylcarbazole-2-acetic acid, 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid, 6-chloro-alpha-Methyl-9H-carbazole-2-acetic acid, Carprofène, (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid
thumb|100px|A 100 Kilogram#SI multiples|mg Rimadyl tablet approximately wide by thick, as sold in the USA.
Key facts
- Drug.PubChem
- 2581
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 460020416
- Drug.image
- Carprofen.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 280
- Drug.alt
- Two-dimensional monochrome diagram showing the structure of the molecule of Carprofen, uing the hexagonal style to depict a chemical compound.
- Drug.caption
- Carprofen molecule
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Rimadyl, others
- Drug.DailyMedID
- Carprofen
- Drug.routes_of_administration
- By mouth, injection
- Drug.ATCvet
- yes
- Drug.ATC_prefix
- M01
- Drug.ATC_suffix
- AE91
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.protein_bound
- High (99%)
via Wikipedia infobox
Research
797 papers- Clinical evaluation of postoperative analgesia, cardiorespiratory parameters and changes in liver and renal function tests of paracetamol compared to meloxicam and carprofen in dogs undergoing ovariohysterectomy.PloS one · 2020
- Efficacy of meloxicam compared with carprofen for treating canine osteoarthritis.The Veterinary record · 2020
- Use of carprofen for the treatment of pain and inflammation in dogs.Journal of the American Veterinary Medical Association · 1997
- Pharmacokinetics and bioavailability of carprofen in sheep.Journal of veterinary pharmacology and therapeutics · 2022
- Carprofen: a new nonsteroidal antiinflammatory drug. Pharmacology, clinical efficacy and adverse effects.Pharmacotherapy · 1987
via PubMed
~6 min read
Encyclopedic overview
9 sectionsContents
- Human use
- Veterinary medicine
- Canine use
- Adverse effects
- Equine use
- Other animal use
- Brands and dosage forms for veterinary use
- References
- External links
thumb|100px|A 100 Kilogram#SI multiples|mg Rimadyl tablet approximately wide by thick, as sold in the USA.
Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the carbazole and propionic acid class that was previously for use in humans and animals but is now only available to veterinarians for prescribing as a supportive treatment for various conditions in animals. Carprofen reduces inflammation by inhibition of COX-1 and COX-2; its specificity for COX-2 varies from species to species. Marketed under many brand names worldwide, carprofen is used as a treatment for inflammation and pain, including joint pain and postoperative pain.
Excerpted from Wikipedia’s “carprofen” article, available under the CC BY-SA 4.0 licence.