cefaclor

Also known as Ceclor, Panacef, Alfatil, CCL, Céfeaclor, Cefaclor anhydrous, Cephaclor, Cefacloro

Cefaclor, sold under the trade name Ceclor among others, is a second-generation cephalosporin antibiotic used to treat certain bacterial infections such as pneumonia and infections of the ear, lung, skin, throat, and urinary tract. It is also available from other manufacturers as a generic.

Chemical data

Formula: C15H14ClN3O4S
Molecular weight: 367.8 g/mol
IUPAC name: (6R,7R)-7-[[(2R)-2-azaniumyl-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)[NH3+])C(=O)[O-])Cl
InChIKey: QYIYFLOTGYLRGG-GPCCPHFNSA-N
XLogP: -1.1
Polar surface area: 142 Å²
H-bond donors: 2
H-bond acceptors: 5
Formal charge: 0

via PubChem

Research

1,949 papers

Cefaclor into the millennium.Journal of chemotherapy (Florence, Italy) · 1999
Cefaclor revisited.Clinical therapeutics · 2000
Evaluation of cefaclor.American journal of hospital pharmacy · 1981
Cefaclor reactions.Pediatric infectious disease · 1985
Cephalexin, Cefaclor, and Ampicillin: Points in the Picture of β-Lactam Cross-Reactivity.The journal of allergy and clinical immunology. In practice · 2022

via PubMed

Wikidata facts

Mass: 367.039355

Show 5 more facts

chemical formula: C₁₅H₁₄ClN₃O₄S
isomeric SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl
canonical SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl
defined daily dose: 1
Commons category: Cefaclor

Sources (6)

via Wikidata · CC0

~6 min read

Article

10 sections

Contents

Medical uses
Spectrum of activity
Cautions and contraindications
Side effects
Pregnancy and breastfeeding
Interactions
Coumarins
Probenecid
Antacids
References

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