cefteram
Sign in to saveCefteram (INN) is a third-generation cephalosporin antibiotic. ==Synthesis== upright=2 The reaction of 7-aminocephalosporanic acid (1) with the methyl-substituted tetrazole (2) gives the intermediate (3). Protection with diazodiphenylmethane (4) produces (5). Amide formation with the thiazole carboxylic acid (6) gives (7), which is deprotected with trifluoroacetic acid to yield cefteram.
Wikidata facts
- Mass
- 479.0794066440001
Show 4 more facts
- Commons category
- Cefteram
- chemical formula
- C₁₆H₁₇N₉O₅S₂
- isomeric SMILES
- Cc1nnn(n1)CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=NOC)/c4csc(n4)N)SC2)C(=O)O
- canonical SMILES
- CC1=NN(N=N1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O
Sources (2)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- Synthesis
- References
Cefteram (INN) is a third-generation cephalosporin antibiotic. ==Synthesis== upright=2 The reaction of 7-aminocephalosporanic acid (1) with the methyl-substituted tetrazole (2) gives the intermediate (3). Protection with diazodiphenylmethane (4) produces (5). Amide formation with the thiazole carboxylic acid (6) gives (7), which is deprotected with trifluoroacetic acid to yield cefteram.
== References ==
Available in 8 languages
via Wikidata sitelinks · CC0