celiprolol
Sign in to saveAlso known as REV 5320, ST-1396, ST1396, (RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea
Celiprolol is a medication in the class of beta blockers, used in the treatment of high blood pressure. It has a unique pharmacology: it is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is also a weak α2 receptor antagonist.
Key facts
- Drug.PubChem
- 2663
- Drug.IUPAC_name
- (RS)-N'-{3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea
- Drug.image
- Celiprolol.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200px
- Drug.chirality
- Racemic mixture
- Drug.bioavailability
- 30-70%
- Drug.elimination_half life
- 5 hours
- Drug.CAS_number
- 56980-93-9
- Drug.ATC_prefix
- C07
- Drug.ATC_suffix
- AB08
- Drug.DrugBank
- DB04846
- Drug.ChemSpiderID
- 2563
- Drug.UNII
- DRB57K47QC
- Drug.KEGG
- D07660
- Drug.ChEMBL
- 27810
- Drug.C
- 20
- Drug.H
- 33
via Wikipedia infobox
Research
550 papers- Celiprolol pneumonitis.The European respiratory journal · 1993
- The Impact of Celiprolol in Vascular Ehlers-Danlos Syndrome: A Systematic Review of Current Evidence.Medical sciences (Basel, Switzerland) · 2025
- Celiprolol in hypertension.American heart journal · 1988
- Celiprolol and sympatho-immune interface in COVID-19.Immunology · 2023
- Celiprolol--a better beta blocker?Drug and therapeutics bulletin · 1992
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 379.247
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₀H₃₃N₃O₄
- World Health Organisation international non-proprietary name
- celiprolol
- canonical SMILES
- CCN(CC)C(=O)NC1=CC(=C(C=C1)OCC(CNC(C)(C)C)O)C(=O)C
- defined daily dose
- 0.2
- significant drug interaction
- fingolimod
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Medical use
- Brand names
- References
- External links
{{Infobox drug | IUPAC_name = (RS)-N'-{3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea | image = Celiprolol.svg | image_class = skin-invert-image | width = 200px | chirality = Racemic mixture
| tradename = | Drugs.com = | pregnancy_category = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “celiprolol” article, available under the CC BY-SA 4.0 licence.