Cofilin 2 (muscle) also known as CFL2 is a protein which in humans is encoded by the CFL2 gene.
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Cofilin 2 (muscle) also known as CFL2 is a protein which in humans is encoded by the CFL2 gene.
==Function== Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN), all of which regulate actin-filament dynamics. The CFL2 gene encodes a skeletal muscle-specific isoform localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).