CHKA
Sign in to saveAlso known as CHK, CK, CKI, EK, choline kinase alpha
Choline kinase alpha is an enzyme that in humans is encoded by the CHKA gene.
In the Vinony graph
Within Vinony's link graph, CHKA is referenced by 14 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Its subject is documented across 4 Wikipedia language editions.
Gene data
CHKA- Name
- choline kinase alpha
- Type
- protein-coding
- Position
- 68,052,848–68,121,449 (−)
- Aliases
- CHK, CK, CKI, EK, NEDMIMS
- Ensembl
- ENSG00000110721
- RefSeq RNA
- NM_001277.3, NM_001376219.1, NM_001376220.1, NM_001376221.1, NM_001376222.1
- RefSeq protein
- NP_001268.2, NP_001363148.1, NP_001363149.1, NP_001363150.1, NP_001363151.1
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
choline kinase alpha
- Symbol
- CHKA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:68,052,848-68,121,449
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CHKA PDB 2cko.png
Show 8 more facts
- HomoloGene ID
- 88575
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1119
- genomic end
- 67888911
- genomic start
- 67820326
- expressed in
- body of stomach
- chromosome
- human chromosome 11
- cytogenetic location
- 11q13.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Clinical significance
- References
- External links
- Further reading
Choline kinase alpha is an enzyme that in humans is encoded by the CHKA gene.
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “CHKA” article, available under the CC BY-SA 4.0 licence.