chlorambucil
Sign in to saveChlorambucil, sold under the brand name Leukeran among others, is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. It is given by mouth.
Research
5,507 papers- Chlorambucil-induced seizures.Cancer · 1997
- Chlorambucil.IARC monographs on the evaluation of the carcinogenic risk of chemicals to man · 1975
- Chlorambucil for patients with primary biliary cirrhosis.The Cochrane database of systematic reviews · 2012
- Chlorambucil lung toxicity.Acta haematologica · 1990
- Chlorambucil.Report on carcinogens : carcinogen profiles · 2002
via PubMed
Article
9 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Mechanism of action
- Limitations to bioavailability
- Chemistry
- History
- References
- External links
Chlorambucil, sold under the brand name Leukeran among others, is a chemotherapy medication used to treat chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, and non-Hodgkin lymphoma. It is given by mouth.
Common side effects include bone marrow suppression. Other serious side effects include an increased long term risk of further cancer, infertility, and allergic reactions. Use during pregnancy often results in harm to the baby. Chlorambucil is in the alkylating agent family of medications. It works by blocking the formation of DNA and RNA.