Structure via PubChem · Public domain (PubChem)
cinolazepam
Sign in to saveAlso known as 7-chloro-5-(2-Fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile, 7-chloro-5-(O-Fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile, 1-(2-Cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one, Cinolazepamum
Cinolazepam (marketed under the brand name Gerodorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as a hypnotic.
Chemical data
- Formula
- C18H13ClFN3O2
- Molecular weight
- 357.8 g/mol
- IUPAC name
- 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-3H-1,4-benzodiazepin-1-yl]propanenitrile
- SMILES
- C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCC#N)O)F
- InChIKey
- XAXMYHMKTCNRRZ-UHFFFAOYSA-N
- XLogP
- 2
- Polar surface area
- 76.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 357.068
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₈H₁₃ClFN₃O₂
- canonical SMILES
- C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCC#N)O)F
- World Health Organisation international non-proprietary name
- cinolazepam
- Commons category
- Cinolazepam
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Cinolazepam (marketed under the brand name Gerodorm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Due to its strong sedative properties, it is primarily used as a hypnotic.
It was patented in 1978 and came into medical use in 1992. Cinolazepam is mainly used in Romania and Slovakia; it not approved for sale in the United States or Canada.
Excerpted from Wikipedia’s “cinolazepam” article, available under the CC BY-SA 4.0 licence.