clocortolone
Sign in to saveAlso known as 9-chloro-6alpha-Fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione, 9-chloro-6alpha-Fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione, Clocortolon, Clocortolona, Clocortolonum
Clocortolone (Cloderm) is a topical steroid. It is used in the form of an ester, clocortolone pivalate, and applied as a cream. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom.
Research
27 papers- Clocortolone Pivalate.2006
- Safety and efficacy of clocortolone pivalate 0.1 percent cream in the treatment of atopic dermatitis, contact dermatitis, and seborrheic dermatitis.Cutis · 1981
- Clocortolone pivalate: a topical corticosteroid with a unique structure.Journal of drugs in dermatology : JDD · 2013
- Clinical utility of clocortolone pivalate for the treatment of corticosteroid-responsive skin disorders: a systematic review.Clinical, cosmetic and investigational dermatology · 2012
- Adherence to clocortolone pivalate cream 0.1% in a pediatric population with atopic dermatitis.Cutis · 2008
via PubMed
~6 min read
Encyclopedic overview
10 sectionsContents
- Pharmacology
- Cream vehicle
- Clinical studies
- Regulation history
- Commercialization
- Manufacturing process
- Commercialization history
- Price listing
- See also
- References
Clocortolone (Cloderm) is a topical steroid. It is used in the form of an ester, clocortolone pivalate, and applied as a cream. It is used for the treatment of dermatitis and is considered a medium-strength corticosteroid. It is unusual among steroids in that it contains a chlorine atom and a fluorine atom.
== Pharmacology == Clocortolone is an upper-mid potency topical corticosteroid formulation. It is rated at a class 4 potency on a scale of 1 (highest potency) to 7 (lowest potency). Most patients are treated with mid-potency topical corticosteroids, for they are an effective medium between safety and efficacy for short and long-term conditions.
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