DDX6
Sign in to saveAlso known as HLR2, P54, RCK, DEAD-box helicase 6, IDDILF, Rck/p54
Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene.
Gene data
DDX6- Name
- DEAD-box helicase 6
- Type
- protein-coding
- Aliases
- HLR2, IDDILF, P54, RCK, Rck/p54
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012].
via MyGene.info
Wikidata facts
- Image
- Protein DDX6 PDB 1vec.png
Show 5 more facts
- HomoloGene ID
- 3238
- exact match
- identifiers.org/ncbigene/1656
- genomic start
- 118747763
- genomic end
- 118791164
- cytogenetic location
- 11q23.3
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Article
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- References
- Further reading
Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.