Also known as S-[2-(ethylsulfanyl)ethyl] O,O-dimethyl thiophosphate, O,O-dimethyl S-(2-(ethylthio)ethyl)phosphorothioate, O,O-dimethyl S-ethylmercaptoethyl thiophosphate, phosphorothioic acid, S-[2-(ethylthio)ethyl] O,O-dimethyl ester, DSM
Demeton-S-methyl is an organic compound with the molecular formula C6H15O3PS2. It was used as an organothiophosphate acaricide and organothiophosphate insecticide. It is flammable. With prolonged storage, Demeton-S-methyl becomes more toxic due to formation of a sulfonium derivative which has greater affinity to the human form of the acetylcholinesterase enzyme, and this may present a hazard in agricultural use.
Demeton-S-methyl is an organic compound with the molecular formula C6H15O3PS2. It was used as an organothiophosphate acaricide and organothiophosphate insecticide. It is flammable. With prolonged storage, Demeton-S-methyl becomes more toxic due to formation of a sulfonium derivative which has greater affinity to the human form of the acetylcholinesterase enzyme, and this may present a hazard in agricultural use.
== History == Demeton-S-methyl was first described in 1950 by Schrader and was widely adopted as a pesticide because of the lower toxicity to humans than the previously used demeton. In its beginning days, it was mostly used together with demeton-O-methyl in an O:S ratio of 70:30. From 1957 onward, only pure demeton-S-methyl was used. Because of its high toxicity and severe toxic effects to humans, demeton-S-methyl is now classified as a highly toxic substance by the World Health Organization and is banned from agricultural use worldwide.
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