Structure via PubChem · Public domain (PubChem)
didesmethylescitalopram
Sign in to saveDidesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic). 'Didesmethylescitalopram' is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.
In the Vinony graph
Vinony's link graph records 409 inbound references to didesmethylescitalopram, and connects out to N-methylserotonin, selective serotonin reuptake inhibitor and tricyclic antidepressant.
It sits within the topics 4-Fluorophenyl compounds, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.
Vinony links it to 5 Wikipedia language editions.
Chemical data
- Formula
- C18H17FN2O
- Molecular weight
- 296.3 g/mol
- IUPAC name
- (1S)-1-(3-aminopropyl)-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
- SMILES
- C1C2=C(C=CC(=C2)C#N)[C@](O1)(CCCN)C3=CC=C(C=C3)F
- InChIKey
- RKUKMUWCRLRPEJ-SFHVURJKSA-N
- XLogP
- 2.3
- Polar surface area
- 59 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 296.132
Show 3 more facts
- canonical SMILES
- C1C2=C(C=CC(=C2)C#N)C(O1)(CCCN)C3=CC=C(C=C3)F
- chemical formula
- C₁₈H₁₇FN₂O
- isomeric SMILES
- C1C2=C(C=CC(=C2)C#N)[C@](O1)(CCCN)C3=CC=C(C=C3)F
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic). 'Didesmethylescitalopram' is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.
== See also == Desmethylcitalopram Desmethylsertraline Desmethylvenlafaxine Norfluoxetine
Excerpted from Wikipedia’s “didesmethylescitalopram” article, available under the CC BY-SA 4.0 licence.