DIDS
Sign in to saveAlso known as 4,4'-diisothiocyanostilbene-2,2'-disulphonic acid, 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid, ABC inhibitor 2, 2,2'-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonic acid), 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, 4,4'-diisothiocyanato-2,2'-stilbenedisulfonic acid
4,4′-Diisothiocyano-2,2′-stilbenedisulfonic acid (DIDS) is an anion exchange inhibitor, blocking reversibly, and later irreversibly, exchangers such as chloride-bicarbonate exchanger.
Research
4,170 papers- DIDS inhibits Vibrio vulnificus cytotoxicity by interfering with TolC-mediated RtxA1 toxin secretion.European journal of pharmacology · 2020
- Molecular Determinant of DIDS Analogs Targeting RAD51 Activity.Molecules (Basel, Switzerland) · 2021
- DIDS inhibits overexpression BAK1-induced mitochondrial apoptosis through GSK3β/β-catenin signaling pathway.Journal of cellular physiology · 2018
- DIDS reduces ischemia/reperfusion-induced myocardial injury in rats.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2015
- Synthesis and biological evaluation of DIDS analogues as efficient inhibitors of RAD51 involved in homologous recombination.Bioorganic & medicinal chemistry letters · 2023
via PubMed
Article · 日本語
4,4'-ジイソチオシアノ-2,2'-スチルベンジスルホン酸（4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, DIDS）は、その構造から明らかなようにイソチオシアネートに分類される化合物の1種である。通常、DIDSと略す。
Abstract from DBpedia / Wikipedia · CC BY-SA