dimetotiazine

Chemical data

Formula

C19H25N3O2S2

Molecular weight

391.6 g/mol

IUPAC name

10-[2-(dimethylamino)propyl]-N,N-dimethylphenothiazine-2-sulfonamide

SMILES

CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C

InChIKey

VWNWVCJGUMZDIU-UHFFFAOYSA-N

XLogP

3.8

Polar surface area

77.5 Ų

H-bond donors

0

H-bond acceptors

6

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

Indications

migraine disorder

via ChEMBL · EBI

• Identification of phenothiazine antihistamines and their metabolites in urine.Archives of toxicology · 1988
• [Clinical use of dimetotiazine (8599RP)].Saishin igaku. Modern medicine · 1967
• [Migraine in childhood and adolescence: a retrospective review of hospital cases].Revista de neurologia · 1995
• Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats.British journal of pharmacology · 1995
• [Effect of KB-2796, a novel calcium channel blocker, on spreading depression in rat hippocampal slices].Nihon yakurigaku zasshi. Folia pharmacologica Japonica · 1998

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

391.139

via Wikidata · CC0