dofetilide
Sign in to saveAlso known as Tikosyn®, UK-68798, beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide, Dofetilidum, Dofetilida
Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 μg of dofetilide. It is not available in Europe or Australia.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 441.139213
- Has use
- medication
Show 9 more facts
- significant drug interaction
- thioridazine
- chemical formula
- C₁₉H₂₇N₃O₅S₂
- medical condition treated
- heart disease
- canonical SMILES
- CN(CCC1=CC=C(C=C1)NS(=O)(=O)C)CCOC2=CC=C(C=C2)NS(=O)(=O)C
- World Health Organisation international non-proprietary name
- dofetilide
- subject has role
- antiarrhythmic agent
- physically interacts with
- Potassium voltage-gated channel subfamily H member 2
- Commons category
- Dofetilide
- legal status (medicine)
- boxed warning
via Wikidata · CC0
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Encyclopedic overview
10 sectionsContents
- Medical uses
- Contraindications
- Adverse effects
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Metabolism
- History
- See also
- References
{{Drugbox | verifiedrevid = 457790505 | IUPAC_name = N-[4-(2-{[2-(4-methane sulfonamidophenoxy)ethyl] (methyl)amino}ethyl)phenyl]methanesulfonamide | image = Dofetilide.svg | image_class = skin-invert-image
| tradename = Tikosyn | Drugs.com = | MedlinePlus = a601235 | pregnancy_category = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “dofetilide” article, available under the CC BY-SA 4.0 licence.