Structure via PubChem · Public domain (PubChem)
Dronedaron
Sign in to saveAlso known as SR-33598B, SR 33589B, SR 33589, SR 33589b, N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-{p-[3-(dibutylamino)propoxy]benzoyl}-5-benzofuranyl)methanesulfonamide
chemische Verbindung
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461091509
- Drug.image
- Dronedarone structure.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Multaq
- Drug.MedlinePlus
- a609034
- Drug.DailyMedID
- Dronedarone
- Drug.pregnancy_AU
- D
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- BD07
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.bioavailability
- 15% (with a high-fat meal)
via Wikipedia infobox
Chemical data
- Formula
- C31H44N2O5S
- Molecular weight
- 556.8 g/mol
- IUPAC name
- N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide
- SMILES
- CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC
- InChIKey
- ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
- XLogP
- 7.2
- Polar surface area
- 97.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2009
- Admin. routes
- oral
- Indications
- cardiac arrhythmia, atrial fibrillation, congestive heart failure, atrial flutter
via ChEMBL · EBI
Research
823 papers- Dronedarone.Drugs of today (Barcelona, Spain : 1998) · 2011
- Dronedarone.Circulation · 2009
- Dronedarone a comprehensive drug profile.Profiles of drug substances, excipients, and related methodology · 2025
- Dronedarone.Drugs · 2009
- Dronedarone vs Sotalol Among Patients With Atrial Fibrillation: A Meta-Analysis of Retrospective Observational Databases.JACC. Clinical electrophysiology · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 556.297094
- Has use
- medication
Show 8 more facts
- medical condition treated
- atrial fibrillation
- significant drug interaction
- ketoconazole
- chemical formula
- C₃₁H₄₄N₂O₅S
- canonical SMILES
- CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC
- World Health Organisation international non-proprietary name
- dronedarone
- defined daily dose
- 0.8
- Commons category
- Dronedarone
- legal status (medicine)
- boxed warning
Sources (6)
via Wikidata · CC0
Article · Deutsch
Dronedaron (Handelsname Multaq) ist der Freiname eines Arzneistoffes, der als Antiarrhythmikum zur Behandlung von Herzrhythmusstörungen eingesetzt wird. Das Medikament wird als 400-mg-Tabletten von Sanofi produziert und vermarktet. Die empfohlene Dosierung ist eine zweimal tägliche Einnahme von 400 mg.
Abstract from DBpedia / Wikipedia · CC BY-SA