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GeneQ17915103· pop 5· linked from 83 articles

Also known as MKPX, PYST2, dual specificity phosphatase 7

gene umano

In the Vinony graph

Within Vinony's link graph, DUSP7 is referenced by 83 other articles, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

Vinony files it under EC 3.1.3 and Genes on human chromosome 3.

Its subject is documented across 4 Wikipedia language editions.

Gene data

DUSP7
Name
dual specificity phosphatase 7
Type
protein-coding
Aliases
MKPX, PYST2

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009].

via MyGene.info

Gene · Ensembl

dual specificity phosphatase 7

Symbol
DUSP7
Biotype
Protein coding
Organism
Homo sapiens
Location
3:52,048,919-52,056,577
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
1468
found in taxon
Homo sapiens
genomic end
52056571
genomic start
52082935
cytogenetic location
3p21.2
Sources (4)

via Wikidata · CC0

Available in 4 languages

via Wikidata sitelinks · CC0

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