EA-4056 is a deadly carbamate nerve agent. It is lethal because it inhibits acetylcholinesterase. Inhibition causes an overly high accumulation of acetylcholine between the nerve and muscle cells. This paralyzes the muscles by preventing their relaxation. The paralyzed muscles include those used for breathing.
{{Chembox | Name = EA-4056 | ImageFile = EA_4056.png | ImageClass = skin-invert-image | ImageFile1 = EA-4056_3D_structure.png | ImageClass1 = bg-transparent | OtherNames = | IUPACName = 1,9-Bis[methyl-2(3-dimethylcarbamoxypyridyl)methylamino]nonane dimethobromide | PIN = N1,N9-Bis({3-[(dimethylcarbamoyl)oxy]pyridin-2-yl}methyl)-N1,N1,N9,N9-tetramethylnonane-1,9-bis(aminium) dibromide | SystematicName = | Section1 = | Section2 = | Section3 = | Section4 = | Section5 = | Section6 = }}
EA-4056 is a deadly carbamate nerve agent. It is lethal because it inhibits acetylcholinesterase. Inhibition causes an overly high accumulation of acetylcholine between the nerve and muscle cells. This paralyzes the muscles by preventing their relaxation. The paralyzed muscles include those used for breathing.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).