乙哌立松

Also known as (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one, Eperisonum, Eperison, Eperisona, Epérisone, Eperisone

化合物

In the Vinony graph

Vinony's link graph records 389 inbound references to 乙哌立松, and connects out to neuromuscular-blocking drug, itch and spasticity.

It is catalogued under topics including 1-Piperidinyl compounds, Aromatic ketones and Chemical articles with multiple CAS registry numbers.

Vinony links it to 10 Wikipedia language editions.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 477167014
Drug.IUPAC_name: (2RS)-1-(4-Ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one
Drug.image: Eperisone.png
Drug.image_class: skin-invert-image
Drug.image2: Eperisone3d.png
Drug.image_class2: bg-transparent
Drug.tradename: Myonal
Drug.legal_status: Rx-only
Drug.routes_of_administration: Oral
Drug.index2_label: HCl
Drug.CAS_number: 64840-90-0
Drug.CAS_number2: 56839-43-1
Drug.UNII: 2M2P0551D3
Drug.UNII2: U38O8U7P6X
Drug.ATC_prefix: M03
Drug.ATC_suffix: BX09

via Wikipedia infobox

Chemical data

Formula: C17H25NO
Molecular weight: 259.4 g/mol
IUPAC name: 1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: Back pain, Low back pain

via ChEMBL · EBI

Research

129 papers

Eperisone-induced immediate hypersensitivity reactions.The Korean journal of internal medicine · 2026
Eperisone-Induced Anaphylaxis: Pharmacovigilance Data and Results of Allergy Testing.Allergy, asthma & immunology research · 2019
Clinical characteristics of eperisone-induced immediate-type hypersensitivity.Asian Pacific journal of allergy and immunology · 2020
Eperisone Hydrochloride, a Muscle Relaxant, Is a Potent P2X7 Receptor Antagonist.Chemical & pharmaceutical bulletin · 2024
Pharmacokinetics of eperisone following oral administration in healthy Korean volunteers.Biopharmaceutics & drug disposition · 2021

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 259.194
Has use: medication

Show 5 more facts

chemical formula: C₁₇H₂₅NO
canonical SMILES: CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2
defined daily dose: 0.15
subject has role: parasympatholytic
Commons category: Eperisone

Sources (3)

via Wikidata · CC0

Article · 中文

乙哌立松（Eperisone，商品名妙纳（Myonal））是一种解痉药。该药以盐酸盐（盐酸乙哌立松）的形式应用于临床。乙哌立松是一种中枢性骨骼肌松弛剂，通过松弛骨骼肌和血管平滑肌起作用，并表现出多种效果，例如减少肌强直、改善体循环和抑制疼痛反射。该药物通过减轻骨骼肌的疼痛、缺血和张力过高来抑制肌强直的恶性循环，从而减轻僵硬和痉挛，并促进肌肉运动，该药还可改善与脑血管疾病或颈椎病相关的头晕和耳鸣。与其他解痉药相比，乙哌立松中枢镇静作用较弱，同时还能促进上肢和下肢的随意运动，而不会降低肌肉力量。因此，该药常被用于康复的初始阶段，并在随后的理疗中作为辅助药物使用。该药由日本卫材制药开发。

Abstract from DBpedia / Wikipedia · CC BY-SA