bone cancer that has material basis in neural crest cells derives from undeveloped, undifferentiated neuroectoderm
via Wikipedia infobox
Ewing sarcoma is a type of pediatric cancer that forms in bone or soft tissue. Symptoms may include swelling and pain at the site of the tumor, fever, and a bone fracture. The most common areas where it begins are the legs, pelvis, and chest wall. In about 25% of cases, the cancer has already spread to other parts of the body at the time of diagnosis. Complications may include a pleural effusion or paraplegia.
It is a type of small round cell sarcoma. The cause of Ewing sarcoma is unknown, most cases appearing to occur randomly. Though not strongly associated with known hereditary cancer syndromes, accumulating evidence suggests a strong inherited risk factor, identifying a genetic component having multiple chromosome loci associated with Ewing sarcoma susceptibility. Sometimes Ewing sarcoma is associated with a germline mutation. The underlying mechanism often involves a genetic change known as a reciprocal translocation. Diagnosis is based on biopsy of the tumor.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).