Structure via PubChem · Public domain (PubChem)
فندیلین
Sign in to saveAlso known as Fendiline
Fendiline is a nonselective calcium channel blocker and coronary vasodilator, originally developed for its anti-anginal and antiarrhythmic properties in the management of coronary heart disease.
Chemical data
- Formula
- C23H25N
- Molecular weight
- 315.5 g/mol
- IUPAC name
- 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
212 papers- Fendiline: a review of its basic pharmacological and clinical properties.Pharmatherapeutica · 1987
- Evaluation of fendiline treatment in VP40 system with nucleation-elongation process: a computational model of Ebola virus matrix protein assembly.Microbiology spectrum · 2024
- Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells.Human & experimental toxicology · 2009
- Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC.International journal of molecular sciences · 2019
- Basic mechanisms underlying prenylamine-induced 'torsade de pointes': differences between prenylamine and fendiline due to basic actions of the isomers.Current medical research and opinion · 1988
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 315.199
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₃H₂₅N
- canonical SMILES
- CC(C1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3
- subject has role
- calcium channel blocker
Sources (2)
via Wikidata · CC0